Bile reflux and bile acids in the progression of gastric intestinal metaplasia

Bile reflux and bile acids in the progression of gastric intestinal metaplasia

Blog Article

Abstract.Gastric intestinal metaplasia (GIM) is a precancerous lesion of gastric cancer (GC) and is considered an irreversible point of progression 1/6th Loose Parts for GC.Helicobacter pylori infection can cause GIM, but its eradication still does not reverse the process.

Bile reflux is also a pathogenic factor in GIM and can continuously irritate the gastric mucosa, and bile acids in refluxed fluid have been widely reported to be Stationery associated with GIM.This paper reviews in detail the relationship between bile reflux and GIM and the mechanisms by which bile acids induce GIM.